Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023

Feyisa Shasho Bayisa; Teshome Demis Nimani

doi:doi:10.11648/j.sjcm.20241303.11

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Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023

Feyisa Shasho Bayisa^*

, Teshome Demis Nimani

Published in Science Journal of Clinical Medicine (Volume 13, Issue 3)

Received: 15 June 2024 Accepted: 4 July 2024 Published: 15 August 2024

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Abstract

Background: Tuberculosis (TB) remains a significant public health concern globally, especially among HIV-positive individuals. The study aimed to investigate the factors associated with mortality among HIV/TB co-infected patients receiving antiretroviral therapy (ART) in Dire Dawa, Ethiopia. Methods: A retrospective follow-up study was conducted at Dilchora Referral Hospital among 434 HIV/TB co-infected patients enrolled in ART from January 2008 to January 2023. Standardized checklist was used for data collection and taken from patient’s medical cards and database system. Binary logistic regression was used to identify baseline factors associated with mortality. Results: The study found a mortality rate of 31% among HIV/TB co-infected patients. Factors such as WHO clinical stage III (AOR: 9.3, 95% CI: 3.03, 28.34) and WHO clinical stage IV (AOR: 11.3, 95% CI: 3.5, 36.34) and underweight and overweight body mass index were (AOR: 2.6, 95% CI: 1.35, 4.83) and (AOR: 21.4, 95% CI: 8.24, 55.5), poor ART adherence (AOR: 4.24, 95% CI: 2.25, 7.98), alcohol consumption (AOR: 3.15, 95%: 1.69, 5.87), and smoking (AOR: 4.12, 95% CI: 2.32, 7.29) were associated with increased odds of mortality. Conclusion: The study underscores the importance of identifying and addressing baseline factors that contribute to mortality in HIV/TB co-infected patients. Interventions targeting factors like clinical staging, adherence to ART, and lifestyle habits could help reduce mortality rates in this population.

Published in	Science Journal of Clinical Medicine (Volume 13, Issue 3)
DOI	10.11648/j.sjcm.20241303.11
Page(s)	38-46
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Mortality, HIV/TB Co-infection, Antiretroviral Therapy, Ethiopia

References

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APA Style

Bayisa, F. S., Nimani, T. D. (2024). Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023. Science Journal of Clinical Medicine, 13(3), 38-46. https://doi.org/10.11648/j.sjcm.20241303.11

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ACS Style

Bayisa, F. S.; Nimani, T. D. Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023. Sci. J. Clin. Med. 2024, 13(3), 38-46. doi: 10.11648/j.sjcm.20241303.11

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AMA Style

Bayisa FS, Nimani TD. Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023. Sci J Clin Med. 2024;13(3):38-46. doi: 10.11648/j.sjcm.20241303.11

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@article{10.11648/j.sjcm.20241303.11,
  author = {Feyisa Shasho Bayisa and Teshome Demis Nimani},
  title = {Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023
},
  journal = {Science Journal of Clinical Medicine},
  volume = {13},
  number = {3},
  pages = {38-46},
  doi = {10.11648/j.sjcm.20241303.11},
  url = {https://doi.org/10.11648/j.sjcm.20241303.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20241303.11},
  abstract = {Background: Tuberculosis (TB) remains a significant public health concern globally, especially among HIV-positive individuals. The study aimed to investigate the factors associated with mortality among HIV/TB co-infected patients receiving antiretroviral therapy (ART) in Dire Dawa, Ethiopia. Methods: A retrospective follow-up study was conducted at Dilchora Referral Hospital among 434 HIV/TB co-infected patients enrolled in ART from January 2008 to January 2023. Standardized checklist was used for data collection and taken from patient’s medical cards and database system. Binary logistic regression was used to identify baseline factors associated with mortality. Results: The study found a mortality rate of 31% among HIV/TB co-infected patients. Factors such as WHO clinical stage III (AOR: 9.3, 95% CI: 3.03, 28.34) and WHO clinical stage IV (AOR: 11.3, 95% CI: 3.5, 36.34) and underweight and overweight body mass index were (AOR: 2.6, 95% CI: 1.35, 4.83) and (AOR: 21.4, 95% CI: 8.24, 55.5), poor ART adherence (AOR: 4.24, 95% CI: 2.25, 7.98), alcohol consumption (AOR: 3.15, 95%: 1.69, 5.87), and smoking (AOR: 4.12, 95% CI: 2.32, 7.29) were associated with increased odds of mortality. Conclusion: The study underscores the importance of identifying and addressing baseline factors that contribute to mortality in HIV/TB co-infected patients. Interventions targeting factors like clinical staging, adherence to ART, and lifestyle habits could help reduce mortality rates in this population.
},
 year = {2024}
}

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TY  - JOUR
T1  - Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023

AU  - Feyisa Shasho Bayisa
AU  - Teshome Demis Nimani
Y1  - 2024/08/15
PY  - 2024
N1  - https://doi.org/10.11648/j.sjcm.20241303.11
DO  - 10.11648/j.sjcm.20241303.11
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 38
EP  - 46
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20241303.11
AB  - Background: Tuberculosis (TB) remains a significant public health concern globally, especially among HIV-positive individuals. The study aimed to investigate the factors associated with mortality among HIV/TB co-infected patients receiving antiretroviral therapy (ART) in Dire Dawa, Ethiopia. Methods: A retrospective follow-up study was conducted at Dilchora Referral Hospital among 434 HIV/TB co-infected patients enrolled in ART from January 2008 to January 2023. Standardized checklist was used for data collection and taken from patient’s medical cards and database system. Binary logistic regression was used to identify baseline factors associated with mortality. Results: The study found a mortality rate of 31% among HIV/TB co-infected patients. Factors such as WHO clinical stage III (AOR: 9.3, 95% CI: 3.03, 28.34) and WHO clinical stage IV (AOR: 11.3, 95% CI: 3.5, 36.34) and underweight and overweight body mass index were (AOR: 2.6, 95% CI: 1.35, 4.83) and (AOR: 21.4, 95% CI: 8.24, 55.5), poor ART adherence (AOR: 4.24, 95% CI: 2.25, 7.98), alcohol consumption (AOR: 3.15, 95%: 1.69, 5.87), and smoking (AOR: 4.12, 95% CI: 2.32, 7.29) were associated with increased odds of mortality. Conclusion: The study underscores the importance of identifying and addressing baseline factors that contribute to mortality in HIV/TB co-infected patients. Interventions targeting factors like clinical staging, adherence to ART, and lifestyle habits could help reduce mortality rates in this population.

VL  - 13
IS  - 3
ER  -

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Author Information

Feyisa Shasho Bayisa

Department of Epidemiology and Biostatistics, School of Public Health, College of Health and Medical Science, Haramaya University, Harar, Ethiopia

Contact Email

http://orcid.org/0009-0005-9676-9117
Teshome Demis Nimani

Department of Epidemiology and Biostatistics, School of Public Health, College of Health and Medical Science, Haramaya University, Harar, Ethiopia

Contact Email

http://orcid.org/0000-0002-8982-9362

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APA Style

Bayisa, F. S., Nimani, T. D. (2024). Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023. Science Journal of Clinical Medicine, 13(3), 38-46. https://doi.org/10.11648/j.sjcm.20241303.11

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ACS Style

Bayisa, F. S.; Nimani, T. D. Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023. Sci. J. Clin. Med. 2024, 13(3), 38-46. doi: 10.11648/j.sjcm.20241303.11

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AMA Style

Bayisa FS, Nimani TD. Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023. Sci J Clin Med. 2024;13(3):38-46. doi: 10.11648/j.sjcm.20241303.11

Copy | Download

@article{10.11648/j.sjcm.20241303.11,
  author = {Feyisa Shasho Bayisa and Teshome Demis Nimani},
  title = {Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023
},
  journal = {Science Journal of Clinical Medicine},
  volume = {13},
  number = {3},
  pages = {38-46},
  doi = {10.11648/j.sjcm.20241303.11},
  url = {https://doi.org/10.11648/j.sjcm.20241303.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20241303.11},
  abstract = {Background: Tuberculosis (TB) remains a significant public health concern globally, especially among HIV-positive individuals. The study aimed to investigate the factors associated with mortality among HIV/TB co-infected patients receiving antiretroviral therapy (ART) in Dire Dawa, Ethiopia. Methods: A retrospective follow-up study was conducted at Dilchora Referral Hospital among 434 HIV/TB co-infected patients enrolled in ART from January 2008 to January 2023. Standardized checklist was used for data collection and taken from patient’s medical cards and database system. Binary logistic regression was used to identify baseline factors associated with mortality. Results: The study found a mortality rate of 31% among HIV/TB co-infected patients. Factors such as WHO clinical stage III (AOR: 9.3, 95% CI: 3.03, 28.34) and WHO clinical stage IV (AOR: 11.3, 95% CI: 3.5, 36.34) and underweight and overweight body mass index were (AOR: 2.6, 95% CI: 1.35, 4.83) and (AOR: 21.4, 95% CI: 8.24, 55.5), poor ART adherence (AOR: 4.24, 95% CI: 2.25, 7.98), alcohol consumption (AOR: 3.15, 95%: 1.69, 5.87), and smoking (AOR: 4.12, 95% CI: 2.32, 7.29) were associated with increased odds of mortality. Conclusion: The study underscores the importance of identifying and addressing baseline factors that contribute to mortality in HIV/TB co-infected patients. Interventions targeting factors like clinical staging, adherence to ART, and lifestyle habits could help reduce mortality rates in this population.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Mortality and Associated Factors Among HIV/TB Co-infected Patients Under ART Clinic in Dire Dawa, Ethiopia, 2023

AU  - Feyisa Shasho Bayisa
AU  - Teshome Demis Nimani
Y1  - 2024/08/15
PY  - 2024
N1  - https://doi.org/10.11648/j.sjcm.20241303.11
DO  - 10.11648/j.sjcm.20241303.11
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 38
EP  - 46
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20241303.11
AB  - Background: Tuberculosis (TB) remains a significant public health concern globally, especially among HIV-positive individuals. The study aimed to investigate the factors associated with mortality among HIV/TB co-infected patients receiving antiretroviral therapy (ART) in Dire Dawa, Ethiopia. Methods: A retrospective follow-up study was conducted at Dilchora Referral Hospital among 434 HIV/TB co-infected patients enrolled in ART from January 2008 to January 2023. Standardized checklist was used for data collection and taken from patient’s medical cards and database system. Binary logistic regression was used to identify baseline factors associated with mortality. Results: The study found a mortality rate of 31% among HIV/TB co-infected patients. Factors such as WHO clinical stage III (AOR: 9.3, 95% CI: 3.03, 28.34) and WHO clinical stage IV (AOR: 11.3, 95% CI: 3.5, 36.34) and underweight and overweight body mass index were (AOR: 2.6, 95% CI: 1.35, 4.83) and (AOR: 21.4, 95% CI: 8.24, 55.5), poor ART adherence (AOR: 4.24, 95% CI: 2.25, 7.98), alcohol consumption (AOR: 3.15, 95%: 1.69, 5.87), and smoking (AOR: 4.12, 95% CI: 2.32, 7.29) were associated with increased odds of mortality. Conclusion: The study underscores the importance of identifying and addressing baseline factors that contribute to mortality in HIV/TB co-infected patients. Interventions targeting factors like clinical staging, adherence to ART, and lifestyle habits could help reduce mortality rates in this population.

VL  - 13
IS  - 3
ER  -

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